Written and sourced by Vincent Wesley Couey, RxGrab founder. Updated .
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Millions of Americans use prescription discount cards every month, yet most people only know one or two options. In 2026, eight distinct platforms compete for your prescription dollars, and the price gaps between them can be staggering. We compared the published prices of all eight cards on five of the most commonly filled prescriptions. Whether you're uninsured, underinsured, or just tired of overpaying at the pharmacy counter, this guide shows exactly where each card wins and loses.
If you're already familiar with the basics and just want the head-to-head between the two market leaders, jump to our dedicated GoodRx vs SingleCare comparison. For a complete strategy guide on paying less for every prescription, see how to save money on prescriptions without insurance.
Every card on this list operates on the same fundamental model: the card company negotiates a pre-discounted rate with pharmacies, prints a BIN/PCN/Group number combination on a coupon, and you present that coupon at the pharmacy counter instead of paying full retail price. The pharmacy gets a small processing fee from the card company on each transaction.
What this means practically:
Mail-order platforms like Cost Plus Drugs and Amazon Pharmacy work differently: they set their own dispensing prices rather than negotiating with third-party chains, which is why they can often undercut everyone else on generics.
Founded 2011. The dominant discount card by name recognition and pharmacy coverage. GoodRx aggregates prices from multiple PBMs (pharmacy benefit managers) and shows you the lowest available price at each pharmacy near you. The free tier covers 70,000+ pharmacies. GoodRx's paid tier, formerly Gold and now sold as GoodRx Companion, is $14.99 a month for an individual and $24.99 for a family, or $9.99 and $16.99 a month when paid yearly (goodrx.com/companion, read 30 October 2026). It adds a second negotiated rate that can beat the free coupon on some drugs. The app is the best-designed in the category. Notable limitation: CVS has had repeated disputes with GoodRx, and some CVS locations don't reliably accept GoodRx coupons.
Free, no membership required. SingleCare consistently ranks as GoodRx's closest competitor on price and has maintained steady acceptance at CVS, a meaningful advantage over GoodRx. Pharmacy network covers 35,000+ locations including CVS, Walgreens, Walmart, Kroger, and most independent pharmacies. No paid tier, no price alerts, no telehealth add-ons. For a deep dive, see our GoodRx vs SingleCare comparison.
Owned by GoodRx since April 2021 (it began as RetailMeNot Rx Saver). Free, no sign-up required. RxSaver uses a different set of PBM negotiations than GoodRx and SingleCare, which means it occasionally surfaces prices that neither competitor matches, particularly on less common generics. Coverage is roughly 35,000+ pharmacies. The interface is less polished than GoodRx but functional. Best used as a third check when GoodRx and SingleCare are close in price.
Launched 2020 as a mail-order pharmacy integrated with Amazon Prime. Prime members get access to Amazon's RxPass program ($5/month, covers 60+ generic medications) and "Prime Savings" discounts on hundreds of other generics. Non-Prime customers can still access Amazon Pharmacy but without the Prime discount tier. Strongest for Prime members who fill multiple maintenance medications monthly, the $5 RxPass can cover an entire month of generics for the price of a coffee. Limitation: mail-order only. Not suitable for same-day prescriptions or controlled substances in most states.
Founded 2022. Cost Plus Drugs operates on a transparent pricing model: manufacturer cost + 15% markup + $5 dispensing fee + shipping (standard starts at $5.25). No PBM negotiations, no middlemen. For many older generics, this formula produces very low prices on 90-day fills. Metformin 1000mg (90 tablets): $6.71. Atorvastatin 20mg (90 tablets): $6.23. Lisinopril 20mg (90 tablets): $6.68. Each includes the $5 fee and excludes shipping (Cost Plus pricing API, read 13 October 2026). Mail-order only. Drug formulary is growing but still doesn't cover all medications. See our full Cost Plus Drugs review.
Owned by UnitedHealth Group / OptumRx. Free to use. Optum Perks is often overlooked but has quietly built one of the strongest discount programs for maintenance medications. The card is accepted at 64,000+ pharmacies, a network that rivals GoodRx. Optum's scale as one of the largest PBMs in the U.S. gives it significant negotiating leverage. Particularly strong at Walgreens. No paid tier.
Free, no sign-up required. ScriptSave is one of the oldest players in the category (founded 1989) and has deep relationships with independent pharmacies and regional chains that other cards don't always cover. If you use a local independent pharmacy, ScriptSave is worth checking, it often has better rates there than GoodRx or SingleCare. Network: 65,000+ pharmacies. The website and app are dated but functional.
Free. Blink Health has a unique model: you pay online before picking up, which locks in the price and speeds up the pharmacy counter transaction. The upfront payment model isn't for everyone (you need to plan ahead), but Blink's pharmacy network covers 35,000+ locations and pricing is competitive. Blink also has a mail-order option. The app was significantly updated in late 2025 and is now much cleaner than prior versions.
| Feature | GoodRx | SingleCare | RxSaver | Amazon Rx | Cost Plus | Optum Perks | ScriptSave | Blink |
|---|---|---|---|---|---|---|---|---|
| Cost | Free / from $9.99mo | Free | Free | Free / $5mo | Free | Free | Free | Free |
| Pharmacy network | 70,000+ | 35,000+ | 35,000+ | Mail-order | Mail-order | 64,000+ | 65,000+ | 35,000+ |
| CVS accepted | Inconsistent | Yes | Yes | No | No | Yes | Yes | Yes |
| Walgreens | Yes | Yes | Yes | No | No | Yes (best) | Yes | Yes |
| Walmart | Yes | Yes | Yes | No | No | Yes | Yes | Yes |
| Costco | Yes | Yes | Yes | No | No | Yes | Yes | Yes |
| Independent pharmacies | Good | Good | Good | No | No | Good | Best | Good |
| Same-day prescriptions | Yes | Yes | Yes | No | No | Yes | Yes | Yes* |
| Controlled substances | Yes | Yes | Yes | Limited | No | Yes | Yes | Yes |
| Mobile app | Best rated | Good | Basic | Yes | Web only | Good | Basic | Good |
| Price alerts | Yes | No | No | No | No | No | No | No |
| Telehealth | GoodRx Care | No | No | Amazon Clinic | No | No | No | No |
*Blink requires pre-payment online; pick-up is same-day at participating pharmacies.
This table shows the prices the programs publish, read on 13 October 2026: Cost Plus Drugs from its pricing API, Walmart from its program list (effective 03/24/2025) and Amazon from its RxPass list. Coupon-card prices are not in it on purpose: GoodRx, SingleCare, RxSaver, Optum Perks, ScriptSave and Blink each show a different price for every ZIP code and pharmacy and none publishes a list, so a printed number would not be one you can rely on. To get a coupon price, look up your drug and ZIP on each card's own site.
| Drug | Cost Plus, 30 count | Cost Plus, 90 count (per 30 days) | Walmart list (30 / 90 days) | Amazon RxPass | Coupon cards |
|---|---|---|---|---|---|
| Atorvastatin 20mg (generic Lipitor) | $5.41 ($10.66 shipped) | $6.23 ($2.08) | Not listed | On the list | Varies by ZIP and pharmacy |
| Metformin 1000mg (generic Glucophage) | $5.57 ($10.82 shipped) | $6.71 ($2.24) | $9 / $24 | Not on the list | Varies by ZIP and pharmacy |
| Lisinopril 20mg (generic Zestril) | $5.56 ($10.81 shipped) | $6.68 ($2.23) | $9 / $24 | On the list | Varies by ZIP and pharmacy |
| Sertraline 100mg (generic Zoloft) | $6.04 ($11.29 shipped) | $8.11 ($2.70) | $9 / $24 | On the list | Varies by ZIP and pharmacy |
| Omeprazole 20mg DR (generic Prilosec) | $5.93 ($11.18 shipped) | $7.78 ($2.59) | Not listed | On the list | Varies by ZIP and pharmacy |
Cost Plus prices include its $5 dispensing fee; standard shipping ($5.25) is extra (Cost Plus pricing API, read 13 October 2026). Walmart prices are from its Prescription Program list effective 03/24/2025; Walmart's 30-day metformin quantity is 60 tablets, so a twice-daily 1000 mg user should compare Cost Plus's 60-count price of $6.14. Amazon RxPass is a flat $5 a month for every eligible medication, requires Prime and is not available with Medicaid or CHIP (pharmacy.amazon.com/rxpass; 62 drugs on the list we read on 13 October 2026).
What the sourced prices show: a single 30-day Cost Plus fill is $5.41 to $6.04 before shipping for all five drugs, because the $5 fee is most of the price, and the 90-count fill brings the same drugs to $2.08 to $2.70 per 30 days. Walmart's list is a flat $9 for metformin, lisinopril and sertraline and does not list atorvastatin or omeprazole. RxPass covers four of the five for one $5 monthly fee, so a Prime member filling several of them pays $5 in total, not per drug. Whether a coupon card beats these depends on your ZIP and pharmacy, which is why the strategy above still holds: compare two or three cards before you fill.
The bigger savings opportunity is the pharmacy you choose, not the card. The same drug with the same GoodRx coupon can vary by several dollars between a CVS, Walgreens, Walmart, and Costco in the same zip code. See our cheapest pharmacy comparison for those numbers.
GoodRx's paid tier, formerly Gold and now sold as GoodRx Companion, adds a second set of negotiated rates. It costs $9.99 a month when paid yearly ($119.88 up front) or $14.99 billed monthly (goodrx.com/companion, read 30 October 2026). The savings per fill below are illustrative assumptions, not measurements; use the member price for your own drugs.
| Scenario | Monthly fills | Assumed saving/fill | Monthly savings | Net after $9.99 (yearly plan) | Net after $14.99 (monthly plan) |
|---|---|---|---|---|---|
| One maintenance medication | 1 | $4.00 | $4.00 | -$5.99 (lose money) | -$10.99 (lose money) |
| Two medications, moderate savings | 2 | $4.00 | $8.00 | -$1.99 (nearly break even) | -$6.99 (lose money) |
| Three medications | 3 | $4.00 | $12.00 | +$2.01 (save money) | -$2.99 (lose money) |
| Three medications, high savings | 3 | $7.00 | $21.00 | +$11.01 (clear winner) | +$6.01 (save money) |
Rule of thumb: the paid tier pays for itself when your fills times the average saving per fill beats the fee: three fills a month need at least $3.33 of saving each on the $9.99 yearly plan, and about $5.00 each on the $14.99 monthly plan. Before subscribing, look up the member price for each of your medications and do the specific math, don't assume it will be worth it.
CVS and GoodRx have had a contentious relationship since at least 2020. CVS has, at various points, refused to honor GoodRx coupons at all CVS locations, restricted GoodRx to certain drug categories, or charged GoodRx users the higher CVS CarePass price instead of the GoodRx rate. As of April 2026, GoodRx works at CVS for many drugs but not all, and the experience varies by location and pharmacist.
If CVS is your preferred pharmacy: use SingleCare, Optum Perks, or ScriptSave. All three have stable, consistent acceptance at CVS. The price difference between GoodRx and SingleCare at CVS is typically minimal (under $1 per fill), so there's no real downside to defaulting to SingleCare there.
If you're self-employed or itemizing deductions, every dollar you spend on prescriptions, whether paid with a discount card or out-of-pocket with insurance, potentially qualifies as a medical expense deduction once you clear the 7.5% AGI threshold. CeoCult covers the full mechanics of medical expense deductions, including which prescription costs qualify and how to document them properly.
Many people using discount cards for chronic medications also take supplements, and some combinations require attention. Health Britannica's guide to drug-supplement interactions covers the most common concerns, including statins with CoQ10, metformin with B12, and SSRIs with St. John's Wort.
Yes, GoodRx, SingleCare, RxSaver, Optum Perks, ScriptSave, and Blink Health all offer free versions with no sign-up required. GoodRx's paid tier, now called Companion (formerly Gold), costs $14.99 a month, or $9.99 a month when paid yearly. Amazon Pharmacy's Prime Savings are free for existing Prime members, and RxPass is $5/month. Cost Plus Drugs charges a $5 dispensing fee plus shipping per order, but there's no membership fee.
You can only use one discount card per transaction, but you can ask the pharmacy technician to try a different card before finalizing the sale. Most pharmacists are willing to run 2-3 cards to find the lowest price. You cannot stack discount cards with insurance on the same fill, it's one or the other per transaction.
GoodRx leads with 70,000+ in-store pharmacy locations. ScriptSave and Optum Perks both claim 65,000+. SingleCare and RxSaver cover 35,000+ each. Amazon Pharmacy and Cost Plus Drugs are mail-order only and don't operate through retail pharmacies.
No. Discount card transactions are processed as cash sales and do not count toward your insurance deductible or annual out-of-pocket maximum. If you're close to meeting your deductible, running the prescription through insurance, even at a higher copay, might make more financial sense for that fill, because it accelerates when your insurance kicks in for other expenses.
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Prescription prices in the United States are set through a documented chain of list prices, pharmacy benefit contracts and federal programs, and the sources below are the primary public records of how that chain works. They are linked so a reader can check a claim here without taking this page's word for it.
This page describes how prescription pricing and discount programs work. It is not medical advice, and what a given person pays depends on their own plan, pharmacy and prescriber.