GILENYA costs a pharmacy a median of $414.71 per unit. Its generic equivalent costs $5.33, which makes the brand 77.9 times the price of the same molecule. That is what the pharmacy pays to acquire it. It is not your price: a dispensing fee and margin sit between this number and your receipt.
At this cost the entire outcome is decided by coverage, prior authorisation and assistance. Nobody pays this out of pocket by choice.
Acquisition cost percentile, 3,439 priced products
This is among the most expensive products in the corpus by unit cost, which is where coverage rather than shopping decides what you pay.
Acquisition cost per unit, CMS's own correspondence
$414.71 against $5.33. The generic bar is drawn to scale, which is why it is barely visible at 77.9x. CMS publishes this correspondence per product, so it is a comparison of the same thing rather than a match on names.
Between the cheapest tenth of listings and the dearest tenth, GILENYA varies by 1.1 times. That is a tight band. Pharmacies are buying it at close to the same price, so a difference in what you are charged is a difference in fees and margin rather than in the drug.
MS Medication Assistance (Multiple Programs). [object Object] Estimated saving: Free MS medications for qualifying patients (brand MS drugs cost $70,000-100,000+/year); generic options cost significantly less.
Every figure here is CMS NADAC, the federal survey of what retail pharmacies pay to acquire a drug. It is public-domain federal data and it is the cleanest available floor. It excludes your dispensing fee, your pharmacy's margin, your insurance design and any discount-card pricing, all of which sit between this number and what you hand over. Nothing here is medical advice.
Source: CMS NADAC (National Average Drug Acquisition Cost), Centers for Medicare & Medicaid Services, dataset generated 2026-07-22. See how GILENYA compares across 385 brand and generic pairs, or look up another drug in our price tools.